As you probably know, it is a bit common that some designs that originated in a different media are changed when making an adaptation, usually to make it easier to animate
Now, check out these model sheet from Mankatsu, it's a dedication to recreat the unique cartoon style of MP
In 2006 to celebrate the 30th anniversary of the long-running gag manga by Osamu Akimoto, Shonen Jump realeased an special Volume called "Chou Kochikame", centered on multiple crossover chapters with other mangas like Golgo 13, Kinnikuman, Dragon Ball and of course, Lupin III.
Something I find very interesting about the original interpretation in the manga is that, apart from the horrible person that Lupin is, he's very kind to children and does not accept that they are related to any type of violence.
The first chapter of Shin Lupin has a very interesting paneling.
Anime - Manga Comparison #ルパン三世
Lupin III: Part 2 Episode 112 - Shin Lupin III: Chapter 31.